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rifampin will lower the level or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unidentified.modafinil will minimize the extent or effect of norgestrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Reasonable CYP3A4 inducers may possibly lessen progestin